Oxidative stress modulates PPAR gamma in vascular endothelial cells.

Abstract

The peroxisome proliferator-activated receptor gamma (PPAR gamma) plays an important role in vascular regulation. However, the impact of oxidative stress on PPAR gamma expression and activity has not been clearly defined. Human umbilical vein endothelial cells (HUVECs) were exposed to graded concentrations of H(2)O(2) for 0.5-72h, or bovine aortic… (More)
DOI: 10.1016/j.freeradbiomed.2010.03.007

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