Oxidative stress is induced in female carriers of X-linked adrenoleukodystrophy.

  title={Oxidative stress is induced in female carriers of X-linked adrenoleukodystrophy.},
  author={Marion Deon and Angela Maria Sitta and Aleth{\'e}a Gatto Barschak and Daniela de Moura Coelho and Thatiana F Terroso and Graziela Oliveira Schmitt and Hector Y C Wanderley and Laura Bannach Jardim and Roberto Giugliani and Moacir Wajner and Carmen Regla Vargas},
  journal={Journal of the neurological sciences},
  volume={266 1-2},
X-linked adrenoleukodystrophy (X-ALD) is a peroxisomal disease biochemically characterized by the accumulation of very long chain fatty acids (VLCFA), particularly hexacosanoic (C26:0) and tetracosanoic acids (C24:0) in different tissues and in biological fluids and clinically characterized by central and peripheral demyelination and adrenal insufficiency. A considerable number of heterozygotes (HTZ) for X-ALD develop neurological symptoms like spinal cord involvement resembling milder forms of… CONTINUE READING
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