Oxidative stress is increased in critically ill patients with acute renal failure.

@article{Himmelfarb2004OxidativeSI,
  title={Oxidative stress is increased in critically ill patients with acute renal failure.},
  author={Jonathan Himmelfarb and Ellen McMonagle and Stephanie Freedman and Jennifer S Klenzak and Elizabeth McMenamin and Phuong Dung Le and Lara Bezas Pupim and T. Alp Ikizler and The PICARD Group},
  journal={Journal of the American Society of Nephrology : JASN},
  year={2004},
  volume={15 9},
  pages={2449-56}
}
Patients with acute renal failure (ARF) experience a high mortality rate. Dysregulated inflammation and altered metabolism may increase oxidative stress in ARF patients. Thirty-eight patients who met the Program to Improve Care in Acute Renal Disease (PICARD) Study inclusion criteria underwent plasma protein oxidation and plasma cytokine measurements. For comparison, similar measurements were also performed in 21 critically ill patients without ARF, 28 patients with ESRD, and 49 healthy… CONTINUE READING

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