Oxidative stress is increased in critically ill patients with acute renal failure.

  title={Oxidative stress is increased in critically ill patients with acute renal failure.},
  author={Jonathan Himmelfarb and Ellen McMonagle and Stephanie Freedman and Jennifer S Klenzak and Elizabeth McMenamin and Phuong Dung Le and Lara Bezas Pupim and T. Alp Ikizler and The PICARD Group},
  journal={Journal of the American Society of Nephrology : JASN},
  volume={15 9},
Patients with acute renal failure (ARF) experience a high mortality rate. Dysregulated inflammation and altered metabolism may increase oxidative stress in ARF patients. Thirty-eight patients who met the Program to Improve Care in Acute Renal Disease (PICARD) Study inclusion criteria underwent plasma protein oxidation and plasma cytokine measurements. For comparison, similar measurements were also performed in 21 critically ill patients without ARF, 28 patients with ESRD, and 49 healthy… CONTINUE READING


Publications citing this paper.
Showing 1-10 of 74 extracted citations

Acute fatal metabolic complications in alkaptonuria

Journal of Inherited Metabolic Disease • 2015
View 7 Excerpts
Highly Influenced

N-acetylcysteine attenuates kidney injury in rats subjected to renal ischaemia-reperfusion.

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association • 2006
View 4 Excerpts
Highly Influenced


Publications referenced by this paper.
Showing 1-10 of 53 references

Hospital-acquired renal insufficiency.

American journal of kidney diseases : the official journal of the National Kidney Foundation • 2002

Plasma aminothiol oxidation in chronic renal failure

J Himmelfarb, E McMenamin, E McMonagle
Kidney Int • 2002

Similar Papers

Loading similar papers…