Oxidative stress is an important component of airway inflammation in mice exposed to cigarette smoke or lipopolysaccharide.

Abstract

1. It was proposed previously that oxidative stress is a main component of the inflammatory process in chronic obstructive pulmonary disease (COPD). Thus, in the present study, we investigated the inflammatory response in mice deficient for the p47(phox) subunit of NADPH oxidase (p47 KO) exposed to cigarette smoke (CS). 2. Exposure of mice to CS elicited an… (More)
DOI: 10.1111/j.1440-1681.2007.04848.x

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