Oxidative stress induced by tert-butylhydroperoxide interferes with the placental transport of glucose: In vitro studies with BeWo cells.

@article{Arajo2013OxidativeSI,
  title={Oxidative stress induced by tert-butylhydroperoxide interferes with the placental transport of glucose: In vitro studies with BeWo cells.},
  author={Jo{\~a}o Ricardo Barbosa Ara{\'u}jo and Ana Cl{\'a}udia Ribeiro Pereira and Ana Correia-Branco and Elisa Keating and F{\'a}tima Martel},
  journal={European journal of pharmacology},
  year={2013}
}
Increased oxidative stress is implicated in the onset and progression of prevalent pregnancy disorders (e.g. gestational diabetes and fetal growth restriction), and in programming the fetus to develop metabolic diseases later in life. Since the molecular mechanisms underlying these effects of oxidative stress are largely unexplored, we aimed to investigate if the placental transport of glucose - the main energetic substrate for the fetus and placenta - is altered by oxidative stress. In a human… CONTINUE READING
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