Oxidative stress in vascular disease: causes, defense mechanisms and potential therapies

@article{Frstermann2008OxidativeSI,
  title={Oxidative stress in vascular disease: causes, defense mechanisms and potential therapies},
  author={Ulrich F{\"o}rstermann},
  journal={Nature Clinical Practice Cardiovascular Medicine},
  year={2008},
  volume={5},
  pages={338-349}
}
  • Ulrich Förstermann
  • Published in
    Nature Clinical Practice…
    2008
  • Medicine
  • Endothelial cells control vascular homeostasis by generating paracrine factors that regulate vascular tone, inhibit platelet function, prevent adhesion of leukocytes, and limit proliferation of vascular smooth muscle. The dominant factor responsible for many of those effects is endothelium-derived nitric oxide (NO). Endothelial dysfunction characterized by enhanced inactivation or reduced synthesis of NO, alone or in combination, is seen in conjunction with risk factors for cardiovascular… CONTINUE READING

    Create an AI-powered research feed to stay up to date with new papers like this posted to ArXiv

    Citations

    Publications citing this paper.
    SHOWING 1-10 OF 282 CITATIONS, ESTIMATED 58% COVERAGE

    Effects of nitrite and nitroxyl on human vascular and platelet function.

    VIEW 4 EXCERPTS
    CITES BACKGROUND
    HIGHLY INFLUENCED

    Advanced age protects microvascular endothelium from aberrant Ca(2+) influx and cell death induced by hydrogen peroxide.

    VIEW 6 EXCERPTS
    CITES BACKGROUND
    HIGHLY INFLUENCED

    Atherosclerotic plaque destabilization: mechanisms, models, and therapeutic strategies.

    VIEW 3 EXCERPTS
    CITES BACKGROUND
    HIGHLY INFLUENCED

    Relative contribution of different l-arginine sources to the substrate supply of endothelial nitric oxide synthase.

    VIEW 3 EXCERPTS
    CITES BACKGROUND

    Bioactive compounds in whole grain wheat

    VIEW 5 EXCERPTS
    CITES BACKGROUND
    HIGHLY INFLUENCED

    FILTER CITATIONS BY YEAR

    2008
    2020

    CITATION STATISTICS

    • 9 Highly Influenced Citations

    • Averaged 24 Citations per year from 2017 through 2019

    References

    Publications referenced by this paper.
    SHOWING 1-10 OF 84 REFERENCES

    Reversal of eNOS uncoupling and upregulation of eNOS expression lowers blood pressure in hypertensive rats

    • H Li
    • J Am Coll Cardiol
    • 2006
    VIEW 1 EXCERPT

    Vascular effects of a common gene variant of extracellular superoxide dismutase in heart failure.