Oxidative stress in traumatic brain injury.

  title={Oxidative stress in traumatic brain injury.},
  author={Ana Elena Rodr{\'i}guez-Rodr{\'i}guez and Juan Jos{\'e} Egea-Guerrero and Francisco Murillo-Cabezas and Antonio Carrillo-Vico},
  journal={Current medicinal chemistry},
  volume={21 10},
Traumatic brain injury (TBI) is a major healthcare concern, constituting a major cause of death and disability throughout the world. Among the factors leading to TBI outcome are biochemical cascades which occur in response to primary and secondary injury. These mechanisms generate oxidative stress, an imbalance between oxidant and antioxidant agents that can result in neural dysfunction and death. After TBI, an assembly of oxidative stress markers (carbonylated proteins, lipid peroxides… CONTINUE READING