Oxidative stress in secondary osteoarthritis: from cartilage destruction to clinical presentation?

@inproceedings{Ziskoven2010OxidativeSI,
  title={Oxidative stress in secondary osteoarthritis: from cartilage destruction to clinical presentation?},
  author={Christoph Ziskoven and Marcus J{\"a}ger and Christoph Zilkens and Wilhelm Bloch and Klara Brixius and Ruediger Krauspe},
  booktitle={Orthopedic reviews},
  year={2010}
}
Due to an increasing life expectance, osteoarthritis (OA) is one of the most common chronic diseases. Although strong efforts have been made to regenerate degenerated joint cartilage, OA is a progressive and irreversible disease up to date. Among other factors the dysbalance between free radical burden and cellular scavenging mechanisms defined as oxidative stress is a relevant part of OA pathogenesis. Here, only little data are available about the mediation and interaction between different… CONTINUE READING
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