Oxidative stress in lens in vivo: Inhibitory effect of caffeine. A preliminary report

@inproceedings{Varma2010OxidativeSI,
  title={Oxidative stress in lens in vivo: Inhibitory effect of caffeine. A preliminary report},
  author={SD Varma and KR Hegde and Svitlana Kovtun},
  booktitle={Molecular vision},
  year={2010}
}
PURPOSE Experiments have been conducted to study the hypothesis that caffeine would inhibit reactive oxygen species induced oxidative stress in the lens in vivo, with implications of attenuating or preventing cataract formation. METHODS Oxidative stress was directly induced by administering 24% galactose diet to young adult rats. The treated group was fed a diet containing 24% galactose + 1% caffeine. Oxidative stress inflicted to the lens was assessed by measurement of glutathione (GSH… CONTINUE READING
Highly Cited
This paper has 30 citations. REVIEW CITATIONS