Oxidative stress in immature brain following experimentally-induced seizures.

@article{Folbergrov2013OxidativeSI,
  title={Oxidative stress in immature brain following experimentally-induced seizures.},
  author={Jaroslava Folbergrov{\'a}},
  journal={Physiological research},
  year={2013},
  volume={62 Suppl 1},
  pages={
          S39-48
        }
}
The existing data indicate that status epilepticus (SE) induced in immature animals is associated with oxidative stress and mitochondrial dysfunction. This has been demonstrated using two models of SE, induced by substances with a different mechanism of action (DL-homocysteic acid and 4-aminopyridine) which suggests that the findings are not model-dependent but they reflect more general phenomenon. Oxidative stress occurring in immature brain during and following seizures is apparently due to… CONTINUE READING

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