Oxidative stress in human immunodeficiency virus infection

  title={Oxidative stress in human immunodeficiency virus infection},
  author={Nicole Israël and Marie Anne Gougerot-Pocidalo},
  journal={Cellular and Molecular Life Sciences CMLS},
Abstract. Infection by the human immunodeficiency virus (HIV-1) causes chronic ongoing inflammation in HIV-1 seropositive individuals as shown by high plasma levels of inflammatory cytokines and production of reactive oxygen intermediates (ROIs). One source of ROIs is provided from the very early stages of HIV infection by activated polymorphonuclear neutrophils. Tat, the viral protein, is also specifically responsible for an endogenous cellular increase of ROI. In this review we also evaluate… 

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