Oxidative stress in diabetes and Alzheimer's disease.

  title={Oxidative stress in diabetes and Alzheimer's disease.},
  author={Venkata Reddy and Xiongwei Zhu and George Perry and Mark A. Smith},
  journal={Journal of Alzheimer's disease : JAD},
  volume={16 4},
Oxidative stress plays a major role in diabetes as well as in Alzheimer's disease and other related neurological diseases. Intracellular oxidative stress arises due to the imbalance in the production of reactive oxygen/reactive nitrogen species and cellular antioxidant defense mechanisms. In turn, the excess reactive oxygen/reactive nitrogen species mediate the damage of proteins and nucleic acids, which have been shown to have direct and deleterious consequences in diabetes and Alzheimer's… CONTINUE READING


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