Oxidative stress in chronic hepatitis C: not just a feature of late stage disease.

@article{Jain2002OxidativeSI,
  title={Oxidative stress in chronic hepatitis C: not just a feature of late stage disease.},
  author={Sanjiv Kumar Jain and Philip W. Pemberton and Alexander Smith and R. F. T. Mcmahon and Peter C Burrows and Ali Aboutwerat and Thomas W. Warnes},
  journal={Journal of hepatology},
  year={2002},
  volume={36 6},
  pages={805-11}
}
BACKGROUND/AIMS Chronic hepatitis C infection is a major world-wide problem, frequently progressing to cirrhosis, liver failure or hepatoma. The pathological mechanisms of disease progression are unclear but oxidant stress may play a role. METHODS Markers of lipid peroxidation, antioxidant status, hepatic fibrogenesis and liver function were measured in blood or urine from 42 chronic hepatitis C patients. Fibrosis was graded histologically in a subgroup of 33 patients. RESULTS The lipid… CONTINUE READING
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