Oxidative stress in childhood type 1 diabetes: Results from a study covering the first 20 years of evolution.

@article{MartnGalln2007OxidativeSI,
  title={Oxidative stress in childhood type 1 diabetes: Results from a study covering the first 20 years of evolution.},
  author={Pilar Mart{\'i}n-Gall{\'a}n and Antonio Abad Carrascosa and Miguel Gussiny{\'e} and Carmen Dom{\'i}nguez},
  journal={Free radical research},
  year={2007},
  volume={41 8},
  pages={919-28}
}
This study aimed to further analyse the potential role of oxidative stress in children and adolescents with type 1 diabetes at clinical onset, during disease progression and when early microvascular complications ( + DC) appeared. Compared with age-matched controls, diabetic patients had greater oxidative damage to lipids, proteins and DNA demonstrated by analysis of plasma and erythrocyte malondialdehyde, carbonyl proteins and leukocyte 8-hydroxy-deoxyguanosine, all of which were significantly… CONTINUE READING

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