Oxidative stress in asphyxiated term infants resuscitated with 100% oxygen.

  title={Oxidative stress in asphyxiated term infants resuscitated with 100% oxygen.},
  author={M{\'a}ximo Vento and Miguel Angel Asensi and Juan Sastre and Ana Lloret and Fernando Garc{\'i}a-Sala and J. Vi{\~n}a},
  journal={The Journal of pediatrics},
  volume={142 3},
OBJECTIVE To test the hypothesis that resuscitation of asphyxiated infants with pure oxygen causes hyperoxemia and oxidative stress.Study design Asphyxiated term newborn infants (n = 106) were randomly resuscitated with room air (RAR = 51) or 100% oxygen (OxR = 55). The Apgar score, time of the first cry, and establishment of a sustained pattern of respiration were recorded. Assays performed included: blood gases; reduced glutathione (GSH) and oxidized glutathione (GSSG) in whole blood… CONTINUE READING


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