Oxidative stress defense and deterioration of growth-arrested Escherichia coli cells.

@article{Dukan1999OxidativeSD,
  title={Oxidative stress defense and deterioration of growth-arrested Escherichia coli cells.},
  author={Sam Dukan and Thomas Nystr{\"o}m},
  journal={The Journal of biological chemistry},
  year={1999},
  volume={274 37},
  pages={26027-32}
}
Analysis of protein carbonylation demonstrates that the stasis-induced catalases and cytoplasmic superoxide dismutases (SOD) have a role in preventing accelerated protein oxidation during growth arrest of Escherichia coli cells. A larger number of proteins are carbonylated in cells lacking cytoplasmic SOD compared with cells lacking catalases, OxyR, or RpoS which, in turn, exhibit a larger number of oxidized proteins than the wild-type parent. Proteins exclusively oxidized during stasis in… CONTINUE READING

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