Oxidative stress contributes to autophagy induction in response to endoplasmic reticulum stress in Chlamydomonas reinhardtii.

@article{PrezMartn2014OxidativeSC,
  title={Oxidative stress contributes to autophagy induction in response to endoplasmic reticulum stress in Chlamydomonas reinhardtii.},
  author={Marta P{\'e}rez-Mart{\'i}n and Mar{\'i}a Esther P{\'e}rez-P{\'e}rez and St{\'e}phane D. Lemaire and Jos{\'e} L Crespo},
  journal={Plant physiology},
  year={2014},
  volume={166 2},
  pages={997-1008}
}
The accumulation of unfolded/misfolded proteins in the endoplasmic reticulum (ER) results in the activation of stress responses, such as the unfolded protein response or the catabolic process of autophagy to ultimately recover cellular homeostasis. ER stress also promotes the production of reactive oxygen species, which play an important role in autophagy regulation. However, it remains unknown whether reactive oxygen species are involved in ER stress-induced autophagy. In this study, we… CONTINUE READING
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