Oxidative stress-associated neuroretinal dysfunction and nitrosative stress in diabetic retinopathy.

@article{Mandal2013OxidativeSN,
  title={Oxidative stress-associated neuroretinal dysfunction and nitrosative stress in diabetic retinopathy.},
  author={Lakshmi Kanta Mandal and Subhadip Choudhuri and Deep Dutta and Bhaskar Mitra and Sunanda Kundu and Imran Hussain Chowdhury and Aditi Sen and Mitali Chatterjee and Basudev Bhattacharya},
  journal={Canadian journal of diabetes},
  year={2013},
  volume={37 6},
  pages={
          401-7
        }
}
OBJECTIVE The present study was intended to investigate whether oxidative stress is the key regulator to alter neuroretinal biochemical homeostasis and in turn aggravate the process of diabetic retinopathy by inducing nitrosative stress in the retinal neurovascular unit. METHODS Peripheral blood mononuclear cell reactive oxygen species level was measured by flow cytometry along with spectrophotometric detection of malondialdehyde (MDA) and glutamate from serum or plasma and a vitreous sample… CONTINUE READING
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