Oxidative stress and the antioxidant enzyme system in the developing brain

  title={Oxidative stress and the antioxidant enzyme system in the developing brain},
  author={So-Yeon Shim and Han-suk Kim},
  booktitle={Korean journal of pediatrics},
Preterm infants are vulnerable to the oxidative stress due to the production of large amounts of free radicals, antioxidant system insufficiency, and immature oligodendroglial cells. Reactive oxygen species (ROS) play a pivotal role in the development of periventricular leukomalacia. The three most common ROS are superoxide (O2(•-)), hydroxyl radical (OH(•)), and hydrogen peroxide (H2O2). Under normal physiological conditions, a balance is maintained between the production of ROS and the… CONTINUE READING
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