Oxidative stress and male reproductive biology.

  title={Oxidative stress and male reproductive biology.},
  author={Robert John Aitken and Mark A. Baker},
  journal={Reproduction, fertility, and development},
  volume={16 5},
Spermatozoa were the first cell type in which the cellular generation of reactive oxygen was demonstrated. This activity has now been confirmed in spermatozoa from all mammalian species examined including the rat, mouse, rabbit, horse, bull and human being. Under physiological circumstances, cellular redox activity is thought to drive the cAMP-mediated, tyrosine phosphorylation events associated with sperm capacitation. In addition to this biological role, human spermatozoa also appear to… CONTINUE READING

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