Oxidative stress and human hypertension: vascular mechanisms, biomarkers, and novel therapies.

@article{Montezano2015OxidativeSA,
  title={Oxidative stress and human hypertension: vascular mechanisms, biomarkers, and novel therapies.},
  author={Augusto C. I. Montezano and Maria Gabriela Dulak-Lis and Sofia Tsiropoulou and Adam P. Harvey and Ana Mar{\'i}a Briones and Rhian M Touyz},
  journal={The Canadian journal of cardiology},
  year={2015},
  volume={31 5},
  pages={631-41}
}
Hypertension is a major cardiovascular risk factor. Of the many processes involved in the pathophysiology of hypertension, vascular damage due to oxidative stress (excess bioavailability of reactive oxygen species [ROS]) is particularly important. Physiologically, ROS regulate vascular function through redox-sensitive signalling pathways. In hypertension… CONTINUE READING