Oxidative stress and genetic and epidemiologic determinants of oxidant injury in childhood asthma.

@article{Ercan2006OxidativeSA,
  title={Oxidative stress and genetic and epidemiologic determinants of oxidant injury in childhood asthma.},
  author={Hulya Ercan and Esra Birben and Evrim Alyamaç Dizdar and Ozlem Keskin and Cağatay Karaaslan and Ozge Uysal Soyer and Raziye Dut and Cansin Sackesen and Tanju H Besler and Omer Kalayci},
  journal={The Journal of allergy and clinical immunology},
  year={2006},
  volume={118 5},
  pages={1097-104}
}
BACKGROUND The factors contributing to the oxidant/antioxidant imbalance in asthma are incompletely understood. OBJECTIVE To determine the factors associated with oxidative stress including asthma severity and the genotype of the antioxidant enzymes. METHODS A total of 196 children with mild asthma, 116 children with moderate-severe asthma, and 2 healthy control groups (187 and 68 children) were included in the study. Plasma levels of malondialdehyde were measured as the indicator of… CONTINUE READING

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