Oxidative stress and free radicals in COPD – implications and relevance for treatment

  title={Oxidative stress and free radicals in COPD – implications and relevance for treatment},
  author={Wolfgang Domej and Karl Oettl and Wilfried Renner},
  booktitle={International journal of chronic obstructive pulmonary disease},
Oxidative stress occurs when free radicals and other reactive species overwhelm the availability of antioxidants. Reactive oxygen species (ROS), reactive nitrogen species, and their counterpart antioxidant agents are essential for physiological signaling and host defense, as well as for the evolution and persistence of inflammation. When their normal steady state is disturbed, imbalances between oxidants and antioxidants may provoke pathological reactions causing a range of nonrespiratory and… CONTINUE READING
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