Oxidative stress and chromium(VI) carcinogenesis.

  title={Oxidative stress and chromium(VI) carcinogenesis.},
  author={Hua Yao and Lan Qian Lancia Guo and Bing-hua Jiang and Jia Luo and Xianglin Shi},
  journal={Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer},
  volume={27 2},
Cr(VI)-containing compounds are known carcinogens that are present in industrial settings and in the environment. The biological mechanisms responsible for the initiation and pregression of diseases resulting from exposure to Cr(VI) are not fully understood. In the last two decades, there has been increasing evidence of the correlation between Cr(VI)-induced generation of reactive oxygen species and carcinogenic actions. This article summarizes the current literature on Cr(VI)-induced… CONTINUE READING

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