Oxidative stress and central cardiovascular regulation. - Pathogenesis of hypertension and therapeutic aspects -.

@article{Hirooka2010OxidativeSA,
  title={Oxidative stress and central cardiovascular regulation. - Pathogenesis of hypertension and therapeutic aspects -.},
  author={Yoshitaka Hirooka and Yoji Sagara and Takuya Kishi and Kenji Sunagawa},
  journal={Circulation journal : official journal of the Japanese Circulation Society},
  year={2010},
  volume={74 5},
  pages={827-35}
}
Oxidative stress is a key factor in the pathogenesis of hypertension and target organ damage, beginning in the earliest stages. Extensive evidence indicates that the pivotal role of oxidative stress in the pathogenesis of hypertension is due to its effects on the vasculature in relation to the development of atherosclerotic processes. It remains unclear, however, whether oxidative stress in the brain, particularly the autonomic nuclei (including the vasomotor center), has an important role in… CONTINUE READING

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