Oxidative stress and autologous immunoglobulin G binding to band 3 dimers in newborn erythrocytes.

@article{Rossi2006OxidativeSA,
  title={Oxidative stress and autologous immunoglobulin G binding to band 3 dimers in newborn erythrocytes.},
  author={Viviana Rossi and Silvia Leoncini and Cinzia Signorini and Giuseppe Buonocore and Patrizia Paffetti and Donatella Tanganelli and Lucia Ciccoli and Mario Comporti},
  journal={Free radical biology & medicine},
  year={2006},
  volume={40 5},
  pages={907-15}
}
Since birth-induced oxidative stress (OS) results in the removal of erythrocytes from the blood stream, we studied the binding of autologous IgG to erythrocyte band 3 dimers (the 170-kDa band, which marks the erythrocytes for removal) in preterm and term newborns and in adults. The 170-kDa band was present in as much as 74% of preterm, in 21% of term newborns, and in 10% of adults. During erythrocyte ageing "in vitro" (0, 24, and 48 h aerobic incubation), the appearance of the band occurred… CONTINUE READING

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