Oxidative stress and apoptosis in homocystinuria patients with genetic remethylation defects.

@article{Richard2013OxidativeSA,
  title={Oxidative stress and apoptosis in homocystinuria patients with genetic remethylation defects.},
  author={Eva Richard and Lourdes R Desviat and Magdalena Ugarte and Bel{\'e}n P{\'e}rez},
  journal={Journal of cellular biochemistry},
  year={2013},
  volume={114 1},
  pages={183-91}
}
Oxidative stress has been described as a putative disease mechanism in pathologies associated with an elevation of homocysteine. An increased reactive oxygen species (ROS) production and apoptosis rate have been associated with several disorders of cobalamin metabolism, particularly with methylmalonic aciduria (MMA) combined with homocystinuria cblC type… CONTINUE READING