Oxidative stress, perturbed calcium homeostasis, and immune dysfunction in Alzheimer’s disease

@article{Mattson2002OxidativeSP,
  title={Oxidative stress, perturbed calcium homeostasis, and immune dysfunction in Alzheimer’s disease},
  author={Mark P. Mattson},
  journal={Journal of NeuroVirology},
  year={2002},
  volume={8},
  pages={539-550}
}
Although Alzheimer’s disease (AD) may not involve a transmissible agent, it does involve a pathogenic process similar to that of transmissible prion disorders (both involve a protein that adopts an abnormal pathogenic conformation in which it self-aggregates, forming amyloid deposits in and surrounding neurons) and viral dementias such as human immunodeficiency virus (HIV) encephalitis. The clinical presentation of patients with AD is dominated by cognitive deficits and emotional disturbances… CONTINUE READING

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