Oxidative stress, chronic inflammation, and telomere length in patients with periodontitis.

@article{Masi2011OxidativeSC,
  title={Oxidative stress, chronic inflammation, and telomere length in patients with periodontitis.},
  author={Stefano Masi and Klelia D. Salpea and Kawa Li and Mohamed H. Parkar and Luigi Nibali and Nikolaos Donos and Kalpesh Jashbhai Patel and Stefano Taddei and John Eric Deanfield and Francesco D'Aiuto and Steve E Humphries},
  journal={Free radical biology & medicine},
  year={2011},
  volume={50 6},
  pages={
          730-5
        }
}
The aim of this study was to determine leukocyte telomere length (LTL) in individuals with periodontitis and controls, exploring its relationship with systemic inflammation and oxidative stress. Five hundred sixty-three participants were recruited for this case-control study: 356 subjects with and 207 subjects without periodontitis. LTL was measured by a qPCR technique from leukocytes' DNA. Global measures of oxidative stress (reactive oxygen metabolites) and biological antioxidant potential in… CONTINUE READING
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