Oxidative injury and antioxidant vitamins E and C in Schizophrenia

  title={Oxidative injury and antioxidant vitamins E and C in Schizophrenia},
  author={Benedicta D'souza and Vivian D'souza},
  journal={Indian Journal of Clinical Biochemistry},
Susceptibility of Schizophrenic patients to lipid peroxidation relative to healthy control subjects was investigated by measuring the malondialdehyde (MDA) levels in plasma. The main finding was that Schizophrenic patients were more susceptible than control subjects to oxidative damage as evident from increased MDA levels in plasma. Antioxidant levels are also depleted in Schizophrenic patients when compared to normal subjects as evident from decreased levels of vitamins E and C in the plasma… CONTINUE READING
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Schizophrenia. In: A Text book of Psychiatry, 4 t" Editon, Jaypee Brothers Medical Publishers Pvt. Ltd, New Delhi, p 51-55

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The oxidative damage to mitochondrial DNA shows age dependent increase in human brain

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