Oxidative deoxyribonucleic acid damage in the eyes of glaucoma patients.

@article{Izzotti2003OxidativeDA,
  title={Oxidative deoxyribonucleic acid damage in the eyes of glaucoma patients.},
  author={Alberto Izzotti and Sergio Claudio Sacc{\`a} and Cristina Cartiglia and Silvio L De Flora},
  journal={The American journal of medicine},
  year={2003},
  volume={114 8},
  pages={638-46}
}
BACKGROUND Little is known about the molecular mechanisms responsible for the development of glaucoma, the leading cause of irreversible blindness worldwide. Some investigators have hypothesized that oxidative damage may be involved. We evaluated oxidative deoxyribonucleic acid (DNA) damage, in terms of 8-hydroxy-2'-deoxyguanosine (8-OH-dG), in the eyes of… CONTINUE READING