Oxidative degradation of hydrocortisone in presence of attapulgite.

Degradation of hydrocortisone in attapulgite suspensions was monitored by high-pressure liquid chromatography and UV spectrophotometry. The rate of oxidative degration of hydrocortisone was accelerated significantly in the presence of attapulgite. In addition, degradation appeared to be composed of two apparent first-order reactions rather than the single… CONTINUE READING