Oxidative Stress as a Critical Factor in Nonalcoholic Fatty Liver Disease Pathogenesis.

  title={Oxidative Stress as a Critical Factor in Nonalcoholic Fatty Liver Disease Pathogenesis.},
  author={Schohraya Spahis and Edgard E. Delvin and J. -M. Borys and {\'E}mile L{\'e}vy},
  journal={Antioxidants & redox signaling},
  volume={26 10},
SIGNIFICANCE Nonalcoholic fatty liver disease (NAFLD), characterized by liver triacylglycerol build-up, has been growing in the global world in concert with the raised prevalence of cardiometabolic disorders, including obesity, diabetes, and hyperlipemia. Redox imbalance has been suggested to be highly relevant to NAFLD pathogenesis. Recent Advances: As a major health problem, NAFLD progresses to the more severe nonalcoholic steatohepatitis (NASH) condition and predisposes susceptible… CONTINUE READING
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