Oxidative Stress and Programmed Cell Death in Yeast

@inproceedings{Farrugia2012OxidativeSA,
  title={Oxidative Stress and Programmed Cell Death in Yeast},
  author={Gianluca Farrugia and Rena Balzan},
  booktitle={Front. Oncol.},
  year={2012}
}
Yeasts, such as Saccharomyces cerevisiae, have long served as useful models for the study of oxidative stress, an event associated with cell death and severe human pathologies. This review will discuss oxidative stress in yeast, in terms of sources of reactive oxygen species (ROS), their molecular targets, and the metabolic responses elicited by cellular ROS accumulation. Responses of yeast to accumulated ROS include upregulation of antioxidants mediated by complex transcriptional changes… CONTINUE READING

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