Oxidative Stress EPR Measurement in Human Liver by Radical-probe Technique. Correlation with Etiology, Histology and Cell Proliferation

@article{Valgimigli2002OxidativeSE,
  title={Oxidative Stress EPR Measurement in Human Liver by Radical-probe Technique. Correlation with Etiology, Histology and Cell Proliferation},
  author={M. Valgimigli and L. Valgimigli and D. Trer{\'e} and S. Gaiani and G. Pedulli and L. Gramantieri and L. Bolondi},
  journal={Free Radical Research},
  year={2002},
  volume={36},
  pages={939 - 948}
}
  • M. Valgimigli, L. Valgimigli, +4 authors L. Bolondi
  • Published 2002
  • Medicine
  • Free Radical Research
  • The role of reactive oxygen species (ROS) in liver disease is controversial. This mostly reflects the difficulties to quantify ROS in vivo, particularly in humans. We aimed to measure the presence of ROS in diseased human liver and identify possible relations between ROS levels and etiology, histology and hepatocyte proliferation. Liver biopsy specimens from 102 individuals: 18 healthy controls and 84 patients (42 HCV chronic hepatitis (CHC), 19 HBV chronic hepatitis (CHB), 7 PBC, 4 PSC, 4 HCV… CONTINUE READING
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