Oxidative DNA damage in prostate cancer patients consuming tomato sauce-based entrees as a whole-food intervention.

@article{Chen2001OxidativeDD,
  title={Oxidative DNA damage in prostate cancer patients consuming tomato sauce-based entrees as a whole-food intervention.},
  author={Lin Chen and Maria Stacewicz-Sapuntzakis and Cisilya Duncan and Rooholiah Sharifi and Luna Ghosh and Richard van Breemen and Diane Ashton and Phyllis E. Bowen},
  journal={Journal of the National Cancer Institute},
  year={2001},
  volume={93 24},
  pages={1872-9}
}
BACKGROUND Human prostate tissues are vulnerable to oxidative DNA damage. The risk of prostate cancer is lower in men reporting higher consumption of tomato products, which contain high levels of the antioxidant lycopene. We examined the effects of consumption of tomato sauce-based pasta dishes on lycopene uptake, oxidative DNA damage, and prostate-specific antigen (PSA) levels in patients already diagnosed with prostate cancer. METHODS Thirty-two patients with localized prostate… CONTINUE READING
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