Oxidation-specific biomarkers, prospective 15-year cardiovascular and stroke outcomes, and net reclassification of cardiovascular events.

@article{Tsimikas2012OxidationspecificBP,
  title={Oxidation-specific biomarkers, prospective 15-year cardiovascular and stroke outcomes, and net reclassification of cardiovascular events.},
  author={S. Tsimikas and P. Willeit and J. Willeit and P. Santer and M. Mayr and Q. Xu and A. Mayr and J. Witztum and S. Kiechl},
  journal={Journal of the American College of Cardiology},
  year={2012},
  volume={60 21},
  pages={
          2218-29
        }
}
  • S. Tsimikas, P. Willeit, +6 authors S. Kiechl
  • Published 2012
  • Medicine
  • Journal of the American College of Cardiology
  • OBJECTIVES This study sought to assess the long-term predictive value and net reclassification for risk of cardiovascular disease (CVD) of biomarkers reflecting oxidation-specific epitopes (OSEs). BACKGROUND OSEs are immunogenic, proinflammatory, and proatherogenic. The long-term predictive value and net reclassification of OSEs for risk of CVD events are not known. METHODS Oxidized phospholipids on apolipoprotein B-100 (OxPL/apoB) and immunoglobulin (Ig)-G (IgG) and IgM autoantibodies to… CONTINUE READING
    Anti-Oxidized LDL Antibodies and Coronary Artery Disease: A Systematic Review
    • 4
    • Open Access

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