Oxidation reactions performed by soluble methane monooxygenase hydroxylase intermediates H(peroxo) and Q proceed by distinct mechanisms.

@article{Tinberg2010OxidationRP,
  title={Oxidation reactions performed by soluble methane monooxygenase hydroxylase intermediates H(peroxo) and Q proceed by distinct mechanisms.},
  author={Christine E. Tinberg and Stephen J Lippard},
  journal={Biochemistry},
  year={2010},
  volume={49 36},
  pages={7902-12}
}
Soluble methane monooxygenase is a bacterial enzyme that converts methane to methanol at a carboxylate-bridged diiron center with exquisite control. Because the oxidizing power required for this transformation is demanding, it is not surprising that the enzyme is also capable of hydroxylating and epoxidizing a broad range of hydrocarbon substrates in addition to methane. In this work we took advantage of this promiscuity of the enzyme to gain insight into the mechanisms of action of H(peroxo… CONTINUE READING

References

Publications referenced by this paper.
Showing 1-10 of 65 references

Comprehensive Handbook of Chemical Bond Energies

Y.-R Luo
Comprehensive Handbook of Chemical Bond Energies • 2007

Hydroxylation of C-H bonds at carboxylate-bridged diiron centres.

Philosophical transactions. Series A, Mathematical, physical, and engineering sciences • 2005

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