Oxidation products of stigmasterol interfere with the action of the female sex hormone 17beta-estradiol in cultured human breast and endometrium cell lines.

@article{Newill2007OxidationPO,
  title={Oxidation products of stigmasterol interfere with the action of the female sex hormone 17beta-estradiol in cultured human breast and endometrium cell lines.},
  author={Heike Newill and Renate Loske and J{\"o}rg Wagner and Christian Johannes and Reinhard L. Lorenz and Leane Lehmann},
  journal={Molecular nutrition & food research},
  year={2007},
  volume={51 7},
  pages={888-98}
}
Phytosterols are constituents of plant membranes and are thus contained in low concentrations in vegetable products as well as at high concentrations in functional food designed to reduce serum cholesterol levels. Similar to ChOL, phytosterols are oxidized chemically in food and by biotransformation in vivo. Although oxyphytosterols have been detected in the serum of healthy human subjects, little is known of their biological activity. Therefore, the estrogenic and antiestrogenic activities of… CONTINUE READING
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