Oxidant stress and adult respiratory distress syndrome.

  title={Oxidant stress and adult respiratory distress syndrome.},
  author={Kenneth L. Brigham},
  journal={The European respiratory journal. Supplement},
Several experimental and theoretical lines of evidence implicate oxidant mechanisms in the diffuse lung injury which leads to the clinical syndrome called the adult respiratory distress syndrome (ARDS). The fact that the injury is characterized by diffuse lung inflammation and that neutrophils can injure lung cells by producing reactive oxygen species provide all of the events necessary for extracellular oxidant stress as an important mechanism of injury. In experimental models and in the… CONTINUE READING