Oxandrolone in AIDS‐wasting myopathy

  title={Oxandrolone in AIDS‐wasting myopathy},
  author={J. Berger and L. Pall and C. Hall and D. Simpson and P. S. Berry and R. Dudley},
  • J. Berger, L. Pall, +3 authors R. Dudley
  • Published 1996
  • Medicine
  • AIDS
  • Objective: To evaluate oxandrolone, an oral anabolic steroid with potent anabolic activity and minimal androgenic effects, for the treatment of AIDS‐associated myopathy and wasting. Methods: In a multicenter, double‐blind study, 63 HIV‐seropositive men with > 10% loss of body weight were randomized to receive either placebo, 5 mg/day oxandrolone, or 15 mg/day oxandrolone for 16 weeks. Body weight, neuromuscular evaluation, and measures of well‐being were repeatedly assessed. Results: Patients… CONTINUE READING
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