Oxalate in renal stone disease: the terminal metabolite that just won't go away

@article{Marengo2008OxalateIR,
  title={Oxalate in renal stone disease: the terminal metabolite that just won't go away},
  author={Susan Ruth Marengo and Andrea M P Romani},
  journal={Nature Clinical Practice Nephrology},
  year={2008},
  volume={4},
  pages={368-377}
}
The incidence of calcium oxalate nephrolithiasis in the US has been increasing throughout the past three decades. Biopsy studies show that both calcium oxalate nephrolithiasis and nephrocalcinosis probably occur by different mechanisms in different subsets of patients. Before more-effective medical therapies can be developed for these conditions, we must understand the mechanisms governing the transport and excretion of oxalate and the interactions of the ion in general and renal physiology… CONTINUE READING

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