Oxalate exposure promotes reinitiation of the DNA synthesis and apoptosis of HK-2 cells, a line of human renal epithelial cells.

@article{Koul2003OxalateEP,
  title={Oxalate exposure promotes reinitiation of the DNA synthesis and apoptosis of HK-2 cells, a line of human renal epithelial cells.},
  author={Sweaty Koul and Sherry Fu and Hari Koul},
  journal={Annals of the New York Academy of Sciences},
  year={2003},
  volume={1010},
  pages={292-5}
}
Oxalate, a metabolic end product, is a major constituent of kidney stones. Previously, we and others have demonstrated that oxalate is toxic to renal epithelial cells. In the present study, we characterized oxalate-induced cell death in HK2 cells, a line of renal epithelial cells from the human kidney. For these studies, HK2 cells were exposed to oxalate… CONTINUE READING