Oxalate-degrading activity in Bifidobacterium animalis subsp. lactis: impact of acidic conditions on the transcriptional levels of the oxalyl coenzyme A (CoA) decarboxylase and formyl-CoA transferase genes.

@article{Turroni2010OxalatedegradingAI,
  title={Oxalate-degrading activity in Bifidobacterium animalis subsp. lactis: impact of acidic conditions on the transcriptional levels of the oxalyl coenzyme A (CoA) decarboxylase and formyl-CoA transferase genes.},
  author={Silvia Turroni and Claudia Bendazzoli and Samuele C F Dipalo and Marco Candela and Beatrice Vitali and Roberto Gotti and Patrizia Brigidi},
  journal={Applied and environmental microbiology},
  year={2010},
  volume={76 16},
  pages={5609-20}
}
Oxalic acid occurs extensively in nature and plays diverse roles, especially in pathological processes. Due to its highly oxidizing effects, hyperabsorption or abnormal synthesis of oxalate can cause serious acute disorders in mammals and can be lethal in extreme cases. Intestinal oxalate-degrading bacteria could therefore be pivotal in maintaining oxalate homeostasis and reducing the risk of kidney stone development. In this study, the oxalate-degrading activities of 14 bifidobacterial strains… CONTINUE READING