Ovulatory effect of interleukin-1 beta on the perfused rat ovary.

  title={Ovulatory effect of interleukin-1 beta on the perfused rat ovary.},
  author={Mats Br{\"a}nnstr{\"o}m and Lin Wang and Robert J. Norman},
  volume={132 1},
The involvement of cytokines derived from ovarian and hematopoietic cells have been suggested in the cyclic events of the ovary. In the present study the effects of two cytokines, interleukin-1 beta (IL-1 beta) and IL-2, on ovulation, steroidogenesis, and prostaglandin (PG) production were explored in rat ovaries perfused in vitro. Ovaries of equine CG (20 IU)-primed immature rats were perfused in a recirculating system for 20 h, and samples were taken for analysis of progesterone, estradiol… CONTINUE READING


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