Ovotestis Disorders of Sexual Development

  title={Ovotestis Disorders of Sexual Development},
  author={Ahmed Hassan Al-Salem},



The newborn with ambiguous genitalia.

The unexpectedness of genital ambiguity in an infant creates an urgent and stressful situation. A logical approach, using a team of specialists together with nursery staff and physicians, allows each

True hermaphroditism

Clinical and laboratory findings and management of four patients with true hermaphroditism are presented and it is shown that atypical genitalia presents significant diagnostic and management challenges.

Regional Variations in the Management of Testicular or Ovotesticular Disorders of Sex Development

The regional variations exist not only between different continents, as already demonstrated by others, but also between Northern, Latin and Eastern European countries, suggesting that ‘one-fits-all’ guidelines for management are not appropriate.

Prenatal diagnosis, sonographic findings and molecular genetic analysis of a 46,XX/46,XY true hermaphrodite chimera

To present the prenatal diagnosis, sonographic findings and, molecular genetic analysis of a 46,XX/46,XY true hermaphrodite chimera and to review the literature.

Early gender assignment in true hermaphroditism.

This classification, based on the appearance of the external genitalia, allows a simple screening and prompt gender assignment in infants identified as true hermaphrodites.

Ovotesticular disorder of sexual development due to 47,XYY/46,XY/45,X mixed gonadal dysgenesis in a phenotypic male presenting as cyclical haematuria: clinical presentation and assessment of long‐term outcomes

A 15‐year‐old having male body habitus, axillary and pubic hair, well‐developed penis and right‐descended testis with history of penoscrotal hypospadias correction, presenting with three episodes of cyclical haematuria is reported, perhaps the first report of 47,XYY/46,XY/45,X causing OTDSD in a phenotypic male.

Unilateral true hermaphrodite with 46,XX/46,XY dispermic chimerism.

A 13 year old female presented with ambiguous external genitalia, right inguinal ovotestis, left ovary, apparently normal Mullerian system, and absent Wolffian system suggested that the patient is a true hermaphrodite dispermic chimera.