Overview of tumor cell chemoresistance mechanisms.


Drug resistance of tumor cells is recognized as the primary cause of failure of chemotherapeutic treatment of most human tumors. Although pharmacological factors including inadequate drug concentration at the tumor site can contribute to clinical resistance, cellular factors play a major role in chemoresistance of several tumors. Although manifestations of… (More)


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@article{Gatti2005OverviewOT, title={Overview of tumor cell chemoresistance mechanisms.}, author={Laura A. Gatti and Franco Zunino}, journal={Methods in molecular medicine}, year={2005}, volume={111}, pages={127-48} }