Overview of the latest treatments for castration-resistant prostate cancer

@article{Bishr2013OverviewOT,
  title={Overview of the latest treatments for castration-resistant prostate cancer},
  author={Mohamed Bishr and Fred Saad},
  journal={Nature Reviews Urology},
  year={2013},
  volume={10},
  pages={522-528}
}
Over the past few years, we have developed an increased understanding of the molecular mechanisms that underlie prostate cancer progression and castration resistance and expanded our repertoire of therapeutic options for castration-resistant prostate cancer (CRPC). Four new agents (cabazitaxel, abiraterone acetate, enzalutamide, and radium-233) have been shown to prolong overall survival in patients with CRPC in the postchemotherapy setting. Targeting the androgen receptor pathway continues to… CONTINUE READING
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