Overview of the biologic markers of breast cancer.

  title={Overview of the biologic markers of breast cancer.},
  author={K Porter-Jordan and Marc E. Lippman},
  journal={Hematology/oncology clinics of North America},
  volume={8 1},
Breast cancer is a complex but increasingly well-understood disease. Clearly, multiple alterations from normal mammary cells are required to achieve a transformed phenotype. Furthermore, there may be several possible alterations within broad categories that will produce the transformations leading to the malignant state. The specific set of alterations within a given cancer may thus provide necessary information about how it is unique and how it may best be treated. Several of the newer… CONTINUE READING