Overview of the Pharmacokinetics of Fluvoxamine

@article{Harten1995OverviewOT,
  title={Overview of the Pharmacokinetics of Fluvoxamine},
  author={Jaap van Harten},
  journal={Clinical Pharmacokinetics},
  year={1995},
  volume={29},
  pages={1-9}
}
  • Jaap van Harten
  • Published 1995
  • Medicine
  • Clinical Pharmacokinetics
  • SummaryThe pharmacokinetics of fluvoxamine, a selective serotonin reuptake inhibitor (SSRI) with antidepressant properties, are well established. After oral administration, the drug is almost completely absorbed from the gastrointestinal tract, and the extent of absorption is unaffected by the presence of food. Despite complete absorption, oral bioavailability in man is ≈ 50% on account of first-pass hepatic metabolism. Peak plasma fluvoxamine concentrations are reached 4 to 12 hours (enteric… CONTINUE READING

    Citations

    Publications citing this paper.
    SHOWING 1-10 OF 34 CITATIONS, ESTIMATED 41% COVERAGE

    In-vitro and in-vivo evaluation of the drug-drug interaction between fluvoxamine and clozapine

    VIEW 5 EXCERPTS
    CITES BACKGROUND
    HIGHLY INFLUENCED

    Clinical impact of fluvoxamine-mediated long QTU syndrome

    VIEW 1 EXCERPT
    CITES BACKGROUND

    The Amount of Fluvoxamine in Milk Is Unlikely to Be a Cause of Adverse Effects in Breastfed Infants

    VIEW 8 EXCERPTS
    CITES BACKGROUND
    HIGHLY INFLUENCED

    Polymorphism of Human Cytochrome P450 2D6 and Its Clinical Significance

    VIEW 38 EXCERPTS
    CITES BACKGROUND
    HIGHLY INFLUENCED

    FILTER CITATIONS BY YEAR

    1999
    2020

    CITATION STATISTICS

    • 5 Highly Influenced Citations